BMB5013143 ECTSQ3EnglishMaster
Cancer Metabolism
FaculteitFaculty of Medical Sciences
NiveauMaster
Studiejaar2026-2027
Beschrijving
Course goals
- understands why deregulated cellular metabolism is a ‘hallmark of cancer’;
- has obtained in-depth knowledge on the molecular mechanisms through which cancer cells can rewire their metabolism;
- can explain how whole body metabolism or the metabolism of adjacent cells can affect cancer cell functions;
- is able to critically read, present and discuss recent research papers;
- is able to make and present a poster which proposes a research project based on recently published articles in this field.
Content
Period (from – till): 15 February - 26 February 2027 (BMS_P3_A)
Lecturers
Dr. Eric Kalkhoven
Prof. dr. Saskia van Mil
Dr. Maria Rodriguez-Colman
Prof. dr. Nanda Verhoeven
Dr. Esther Zaal
Guest speaker
Additional supervisors from UMCU Center for Molecular Medicine and Genetics department, section Metabolic Diagnostics
Course content
The course Cancer metabolism centers on the idea that cellular metabolic networks support key aspects of cancer cell function. Lectures and tutorials in the first week discuss the various underlying molecular mechanisms, including the classical ‘Warburg effect’ and other metabolic rewiring proccesses, oncometabolites, reactive oxygen species (ROS) and lipids, and the link(s) with epigenetics. The course will also illustrate how altered metabolism, either in the whole body or in cells adjacent to a tumour, can affect cancer cell functions. Various experimental anad analytical approaches including metabolomics will be covered. Presentations by students and a written exam are part of this week. In the second week students have to develop a new research aim in a small group (3-5 students) and present this as a poster.
Literature/study material used:
Recent reviews and original articles
Registration:
You can register for this course via Osiris Student. More information about the registration procedure can be found here on the Students' site.
The maximum number of participants in total is 40. CSDB students have priority until a max of 40 participants.
Mandatory for students in Master’s programme:
CSDB: can be part of the 15 EC Theoretical Courses
Optional for students from other GSLS Master's programmes:
Yes
Prerequisite knowledge:
A bachelor degree in Biomedical Sciences or equivalent. The student must have thorough knowledge of basic molecular and cellular biology, taught from textbooks like Molecular Biology of the Cell (“Alberts”). Students should be proficient in English, and be able to quickly grasp the main points of a research paper.
Prerequisite knowledge:
A bachelor degree in Biomedical Sciences or equivalent. The student must have thorough knowledge of basic biochemistry, cell biology and physiology. Basic concepts of metabolism will be recapitulated at the beginning of the course. Students should be proficient in English, and be able to quickly grasp the main points of a research paper.
Lecturers
Dr. Eric Kalkhoven
Prof. dr. Saskia van Mil
Dr. Maria Rodriguez-Colman
Prof. dr. Nanda Verhoeven
Dr. Esther Zaal
Guest speaker
Additional supervisors from UMCU Center for Molecular Medicine and Genetics department, section Metabolic Diagnostics
Course content
The course Cancer metabolism centers on the idea that cellular metabolic networks support key aspects of cancer cell function. Lectures and tutorials in the first week discuss the various underlying molecular mechanisms, including the classical ‘Warburg effect’ and other metabolic rewiring proccesses, oncometabolites, reactive oxygen species (ROS) and lipids, and the link(s) with epigenetics. The course will also illustrate how altered metabolism, either in the whole body or in cells adjacent to a tumour, can affect cancer cell functions. Various experimental anad analytical approaches including metabolomics will be covered. Presentations by students and a written exam are part of this week. In the second week students have to develop a new research aim in a small group (3-5 students) and present this as a poster.
Literature/study material used:
Recent reviews and original articles
Registration:
You can register for this course via Osiris Student. More information about the registration procedure can be found here on the Students' site.
The maximum number of participants in total is 40. CSDB students have priority until a max of 40 participants.
Mandatory for students in Master’s programme:
CSDB: can be part of the 15 EC Theoretical Courses
Optional for students from other GSLS Master's programmes:
Yes
Prerequisite knowledge:
A bachelor degree in Biomedical Sciences or equivalent. The student must have thorough knowledge of basic molecular and cellular biology, taught from textbooks like Molecular Biology of the Cell (“Alberts”). Students should be proficient in English, and be able to quickly grasp the main points of a research paper.
Prerequisite knowledge:
A bachelor degree in Biomedical Sciences or equivalent. The student must have thorough knowledge of basic biochemistry, cell biology and physiology. Basic concepts of metabolism will be recapitulated at the beginning of the course. Students should be proficient in English, and be able to quickly grasp the main points of a research paper.
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